Diabetes Mellitus

1. Diabetes Mellitus

• Pathogenesis
• Diagnosis of DM
• Drugs for Diabetes
• Types of Diabetes

2. Insulin

• Synthesis
• Pattern of Insulin secretion
• Injectable insulin 5 types
• Diabetic patient insulin given as Bolus and Basal insulin
• Mixtard insulin
• Glargine and Degludec
• Graph of Insulin actions 
• Preparation of Insulin 
• Structure of Insulin---> LAG and regular insulin structure 
• Uses of Insulin
• Insulin pumps
• Nasal Insulin( Inhaler...eg. Afreeza)
• Adverse effects of Insulin
• Sites of subcutaneous Insulin Injections

3. Acute complications of Diabetes

4. Treatment of Hyperkalemia

OHA/AHA

1. Acting at Pancreas---> Smart MAID

2. Acting at Peripheral Organs ---> BATS 

3. Sulfonylureas

• 1st gen end with amide
• 2nd gen start with Gali
• ROA  and Side effects