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Saturday, August 24, 2024

CELL AND INTEGRATION OF METABOLISM 

Q. The marker enzyme of microsomes is? 
a. Galactosyl Transferase 
b. Cathepsin 
c. Lactate Dehydrogenase 
d. Glucose-6-Phosphatase 

Explanation: Microsome is endoplasmic reticulum; has Glucose-6-phosphatase performs a part of gluconeogenesis. Galactosyl Transferase is present in golgi complex; involved in glycoprotein synthesis. Cathepsin are proteases and enzyme markers of lysosomes. Lactate Dehydrogenase: Enzyme of Glycolysis and marker for cytoplasm. PYO: FMGE 2023 PYQ: FMGE 2020 Marker Enzymes (00:02:15 S no. Organelle Marker Enzyme Nucleus Endoplasmic Reticulum Golgi Complex Replication-DNA polymerase Transcription-RNA polymerase Glucose-6-Phosphatase Galactosyl transferase For OM -Monoamine oxidase inner membrane - ATP synthase / Mitochondrial o Outer Membrane (OM) o Inner Membrane Succinate dehydrogenase Lysosome Cytoplasm Cathepsin Lactate dehydrogenase Catalase Peroxisome: o Very long chain fatty acid oxidation, concerned with ether lipid synthesis (Plasmalogen). o Related to alpha oxidation of BCFA (defect leads to Refsum's Disease). Q. Cytoplasmic proteins are synthesized in? a. Ribosomes b. Nucleus c. Smooth Endoplasmic Reticulum d. Rough Endoplasmic Reticulum Rough Endoplasmic Reticulum: Protein synthesis. Smooth Endoplasmic Reticulum: Steroid synthesis. All protein synthesis is initiated by a free ribosome.

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